ABSTRACT
Following the breakout of the novel coronavirus disease 2019 (COVID‐19), the government of India was forced to prohibit all forms of human movement. It became important to establish and maintain a supply of commodities in hotspots and containment zones in different parts of the country. This study critically proposes new exponential similarity measures to understand the requirement and distribution of commodities to these zones during the rapid spread of novel coronavirus (COVID‐19) across the globe. The primary goal is to utilize the important aspect of similarity measures based on exponential function under Pythagorean fuzzy sets, proposed by Yager. The article aims at finding the most required commodity in the affected areas and ensures its distribution in hotspots and containment zones. The projected path of grocery delivery to different residences in containment zones is determined by estimating the similarity measure between each residence and the various necessary goods. Numerical computations have been carried out to validate our proposed measures. Moreover, a comparison of the result for the proposed measures has been carried out to prove the efficacy.
ABSTRACT
Following the breakout of the novel coronavirus disease 2019 (COVID-19), the government of India was forced to prohibit all forms of human movement. It became important to establish and maintain a supply of commodities in hotspots and containment zones in different parts of the country. This study critically proposes new exponential similarity measures to understand the requirement and distribution of commodities to these zones during the rapid spread of novel coronavirus (COVID-19) across the globe. The primary goal is to utilize the important aspect of similarity measures based on exponential function under Pythagorean fuzzy sets, proposed by Yager. The article aims at finding the most required commodity in the affected areas and ensures its distribution in hotspots and containment zones. The projected path of grocery delivery to different residences in containment zones is determined by estimating the similarity measure between each residence and the various necessary goods. Numerical computations have been carried out to validate our proposed measures. Moreover, a comparison of the result for the proposed measures has been carried out to prove the efficacy.
ABSTRACT
Pulmonary diseases, driven by pollution, industrial farming, vaping, and the infamous COVID-19 pandemic, lead morbidity and mortality rates worldwide. Computational biomechanical models can enhance predictive capabilities to understand fundamental lung physiology; however, such investigations are hindered by the lung's complex and hierarchical structure, and the lack of mechanical experiments linking the load-bearing organ-level response to local behaviors. In this study we address these impedances by introducing a novel reduced-order surface model of the lung, combining the response of the intricate bronchial network, parenchymal tissue, and visceral pleura. The inverse finite element analysis (IFEA) framework is developed using 3-D digital image correlation (DIC) from experimentally measured non-contact strains and displacements from an ex-vivo porcine lung specimen for the first time. A custom-designed inflation device is employed to uniquely correlate the multiscale classical pressure-volume bulk breathing measures to local-level deformation topologies and principal expansion directions. Optimal material parameters are found by minimizing the error between experimental and simulation-based lung surface displacement values, using both classes of gradient-based and gradient-free optimization algorithms and by developing an adjoint formulation for efficiency. The heterogeneous and anisotropic characteristics of pulmonary breathing are represented using various hyperelastic continuum formulations to divulge compound material parameters and evaluate the best performing model. While accounting for tissue anisotropy with fibers assumed along medial-lateral direction did not benefit model calibration, allowing for regional material heterogeneity enabled accurate reconstruction of lung deformations when compared to the homogeneous model. The proof-of-concept framework established here can be readily applied to investigate the impact of assorted organ-level ventilation strategies on local pulmonary force and strain distributions, and to further explore how diseased states may alter the load-bearing material behavior of the lung. In the age of a respiratory pandemic, advancing our understanding of lung biomechanics is more pressing than ever before.